Thermo Fisher Scientific Neurogenin 1 Polyclonal Antibody
Neurogenin 1 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, 인간과 마우스 시료에 반응합니다. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Not specified
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 31–60 from the N-terminal region of human Neurogenin 1 (NeuroG1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2149375 |
Target Information
Neurogenin 1 (NeuroG1) is a basic helix-loop-helix (bHLH) transcription factor involved in determining cell type during development. It plays dual roles in cell-fate specification: promoting neurogenesis and inhibiting astrocyte differentiation. NeuroG1 acts as a transcriptional activator for neuronal genes while inhibiting astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex and suppressing STAT transcription factors essential for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-11890_Neurogenin_1_Q92886-1_Rabbit.svg, PA5-11890_Neurogenin_1_Q92886-1_Rabbit_PDP.jpeg)
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