Thermo Fisher Scientific UCP3 Recombinant Rabbit Monoclonal Antibody (10I0J9)
Thermo Fisher의 UCP3 Recombinant Rabbit Monoclonal Antibody(클론 10I0J9)는 Western blot 및 ELISA에 적합합니다. 인간 UCP3의 200-300 아미노산 서열 기반 합성 펩타이드로부터 제작되었으며, 고순도의 Protein A 정제 항체입니다. -20°C에서 보관하며 반복 동결/해동은 피해야 합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10I0J9 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 200–300 of human UCP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.25 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
YDILKEKLLD YHLLTDNFPC HFVSAFGAGF CATVVASPVD VVKTRYMNSP PGQYFSPLDC MIKMVAQEGP TAFYKGFTPS FLRLGSWNVV MFVTYEQLKR A
Target Information
The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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