Thermo Fisher Scientific CHD1L Recombinant Rabbit Monoclonal Antibody (3C1O9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

3C1O9

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 700-800 of human CHD1L (NP_004275) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHD1L,uniProtId:Q86WJ1-1,ncbiNodeId:9606,antigenRange:700-800,antigenLength:897,antigenImageFileName:MA5-42673_CHD1L_Q86WJ1-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42673_CHD1L_Q86WJ1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911814

Product Specific Information

Positive test controls include: HepG2.

Immunogen sequence: GEESSAELDY QDPDATSLKY VSGDVTHPQA GAEDALIVHC VDDSGHWGRG GLFTALEKRS AEPRKIYELA GKMKDLSLGG VLLFPVDDKE SRNKGQDLLA L

Target Information

In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.