Thermo Fisher Scientific ZPR1 Recombinant Rabbit Monoclonal Antibody (10V1A2)
ZPR1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제 제품으로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 10V1A2 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 360–459 of human ZNF259 (O75312) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911811 |
Product Specific Information
Positive test controls include mouse brain.
The target is usually found in the following locations: Cajal body, cell projection, cytoplasm, nucleus, axon, gem, growth cone, nucleolus, and perinuclear region.
Immunogen sequence:
DIRELVTKNP FTLGDSSNPG QTERLQEFSQ KMDQIIEGNM KAHFIMDDPA GNSYLQNVYA PEDDPEMKVE RYKRTFDQNE ELGLNDMKTE GYEAGLAPQR
Target Information
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells.
It interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth.
Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.
[Provided by RefSeq, Nov 2015]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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