Thermo Fisher Scientific DAB1 Polyclonal Antibody
Goat에서 유래한 DAB1 폴리클로날 항체로, Western blot과 Immunoprecipitation에 사용 가능. Mouse Dab1의 1–179 아미노산 구간을 기반으로 제작됨. 액상 형태이며 1 mg/mL 농도. 신경 발달 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunoprecipitation (IP) | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | GST fusion protein, corresponding to amino acids 1–179 of Mouse Dab1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2230309 |
Product Specific Information
Recommended positive controls:
- 293 cells transfected with Dab1 HA tag IP
- Dab1 Knockout brain p14 lysate
- Dab1 Wild Type brain p14 lysate
Target Information
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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