Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI6B3), TrueMAB
CDKN2C 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 최적화되어 있습니다. 정제된 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 세포주기 조절 연구 및 CDK 억제 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B3 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CDKN2C gene encodes a member of the INK4 family of cyclin-dependent kinase inhibitors.
This protein interacts with CDK4 or CDK6 to prevent kinase activation, regulating cell cycle G1 progression.
Ectopic expression suppresses human cell growth correlated with wild-type RB1 function.
Knockout mouse studies suggest roles in spermatogenesis regulation and tumor suppression.
Two alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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