Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI6D3), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The CDKN2C gene encodes a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein interacts with CDK4 or CDK6 to prevent activation of CDK kinases, thereby regulating cell cycle progression at the G1 phase.
Ectopic expression suppresses cell growth in correlation with wild-type RB1 function. Knockout mouse studies indicate roles in regulating spermatogenesis and suppressing tumorigenesis. Two alternatively spliced transcript variants encode the same protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.