Thermo Fisher Scientific CDKN2C Monoclonal Antibody (OTI6D3), TrueMAB
CDKN2C 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 최적화됨. 인간 단백질에 반응하며, 동결건조 형태로 제공. PBS 완충액에 8% 트레할로스 포함, 보존제 무첨가. -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D3 |
| Immunogen | Full length human recombinant protein of human CDKN2C produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The CDKN2C gene encodes a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein interacts with CDK4 or CDK6 to prevent activation of CDK kinases, thereby regulating cell cycle progression at the G1 phase.
Ectopic expression suppresses cell growth in correlation with wild-type RB1 function. Knockout mouse studies indicate roles in regulating spermatogenesis and suppressing tumorigenesis. Two alternatively spliced transcript variants encode the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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