Thermo Fisher Scientific MEK6 Polyclonal Antibody
MEK6 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, WB, ICC/IF, IP 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태이며, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific MEK6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the sequence of human MKK6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10979180 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
MKK6 (MEK6, MAP2K6) is a member of the dual specificity protein kinase family, functioning as a mitogen-activated protein (MAP) kinase kinase. MAP kinases act as integration points for multiple biochemical signals. MKK6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As a key component of the p38 MAP kinase-mediated signal transduction pathway, it participates in cellular processes such as stress-induced cell cycle arrest, transcription activation, and apoptosis.
Tissue specificity: Isoform 2 is expressed only in skeletal muscle, while Isoform 1 is found in skeletal muscle, heart, and to a lesser extent in liver or pancreas.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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