Thermo Fisher Scientific PTH1R Monoclonal Antibody (4D2)
인간 PTH1R 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 비결합형 액상 형태로 제공되며, 단기 4°C·장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D2 |
| Immunogen | Purified recombinant fragment of human PTH1R expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10982198 |
Product Specific Information
MA5-15676 targets PTH1R in indirect ELISA, IF, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human PTH1R expressed in E. coli.
MA5-15676 detects PTH1R, which has a predicted molecular weight of approximately 66 kDa.
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family.
It acts as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH).
Activation of this receptor triggers G protein-mediated signaling pathways involving adenylyl cyclase and phosphatidylinositol-calcium second messenger systems.
Defects in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis.
PTH1R is expressed in bone, breast, brain, colon, gastrointestinal tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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