Thermo Fisher Scientific COPG Polyclonal Antibody
COPG 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, Affinity chromatography로 정제되었습니다. PBS와 50% glycerol buffer에 보관되며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COPG1 (Accession Q9Y678), corresponding to amino acid residues T718–M768 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899677 |
Product Specific Information
Antibody detects endogenous levels of total COPG.
Target Information
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It mediates biosynthetic protein transport from the ER through the Golgi to the trans-Golgi network. The coatomer complex is essential for budding from Golgi membranes and retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, it is recruited by membranes associated with ADP-ribosylation factors (ARFs), influencing Golgi integrity and LDL receptor recycling. It also regulates lipid homeostasis by controlling PLIN2 and PLIN3 presence at lipid droplets and promoting PNPLA2-mediated lipolysis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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