Thermo Fisher Scientific COPS2 Polyclonal Antibody
Thermo Fisher Scientific의 COPS2 Polyclonal Antibody는 Human, Mouse, Rat에 반응하는 Rabbit IgG 기반 항체입니다. WB, IHC(P), ICC/IF 등 다양한 응용에 사용 가능하며, 고순도 Affinity chromatography 정제 및 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COPS2 (Accession P61201), corresponding to amino acid residues D187–I237 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899678 |
Product Specific Information
Antibody detects endogenous levels of total COPS2.
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+) as electron acceptors. Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent forms located in the mitochondrial matrix, and two NADP(+)-dependent forms, one mitochondrial and one cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer composed of two alpha, one beta, and one gamma subunit. The encoded protein represents the beta subunit of one NAD(+)-dependent isozyme. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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