Thermo Fisher Scientific ERK2 Polyclonal Antibody
ERK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, ICC/IF, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. 액상 형태로 고순도 친화 크로마토그래피 정제. 세포 내 MAPK 경로 연구에 적합.
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Thermo Fisher Scientific ERK2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human ERK2 (NP_0027363) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.29 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804106 |
Product Specific Information
Immunogen sequence:
LNSKGYTKSI DIWSVGCILA EMLSNRPIFP GKHYLDQLNH ILGILGSPSQ EDLNCIINLK ARNYLLSLPH KNKVPWNRLF PNADSKALDL LDKMLTFNPH K
Positive Samples: HeLa, Jurkat, Mouse brain, Mouse spleen, Rat brain, Rat spinal cord
Cellular Location: Cytoplasm, Nucleus, Centrosome, Cytoskeleton, Microtubule organizing center, Spindle
Target Information
MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. Activation of this kinase requires phosphorylation by upstream kinases. Upon activation, ERK2 translocates to the nucleus of stimulated cells where it phosphorylates nuclear targets.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
제품 이미지
(이미지 파일명: PA5-87382_ERK2_P28482-1_Rabbit.svg, PA5-87382_ERK2_P28482-1_Rabbit_PDP.jpeg)
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