
Thermo Fisher Scientific TOB1 Polyclonal Antibody
TOB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 Mouse 종에 반응. Protein A로 정제된 액상 형태, 1.0 mg/mL 농도. -20°C 보관, 연구용 전용.
- 판매단위
- pk
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Thermo Fisher Scientific TOB1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1.25 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of mouse TOB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691407 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Pig: 93%; Rat: 93%
Target Information
This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that regulate cell growth. When exogenously expressed, this protein suppresses cell growth in tissue culture. It is phosphorylated by a serine/threonine kinase, 90 kDa ribosomal S6 kinase.
Interactions with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product (p185) interfere with growth suppression.
This protein inhibits T cell proliferation and transcription of cytokines and cyclins. It interacts with mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity, inhibiting interleukin 2 transcription in T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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