Thermo Fisher Scientific Phospho-GSK3-beta (Ser9) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (IHC)

1:50-1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit

Class

Polyclonal

Type

Antibody

Immunogen

Peptide sequence that includes phosphorylation site of Serine 9 (T-T-S(p)-F-A) derived from Human GSK3 beta and conjugated to KLH. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GSK3B,uniProtId:P49841-1,ncbiNodeId:9606,antigenRange:7-11,antigenLength:420,antigenImageFileName:43002-100UL_GSK3B_P49841-1_Rabbit.svg,antigenImageFileNamePDP:43002-100UL_GSK3B_P49841-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:GSK3B,uniProtId:P18266-1,ncbiNodeId:10114,antigenRange:7-11,antigenLength:420,antigenImageFileName:43002-100UL_GSK3B_P18266-1_Rabbit.svg,antigenImageFileNamePDP:43002-100UL_GSK3B_P18266-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

Dulbecco`s PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.