Thermo Fisher Scientific ATG13 Polyclonal Antibody
ATG13 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, Western blot 및 ELISA에 적합합니다. 인간에서 반응하며, 고순도 affinity chromatography로 정제된 액상 항체입니다. -20°C 보관, 연구용 전용.
- 카탈로그번호
- 600-401-C50x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ATG13 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
ELISA
- Tested Dilution: 1:220,000–1:250,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared by repeated immunizations with a synthetic peptide corresponding to the S318 region of ATG13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening.
Aliquot contents and freeze at -20°C or below for extended storage.
Avoid cycles of freezing and thawing.
Centrifuge product if not completely clear after standing at room temperature.
Stable for several weeks at 4°C as an undiluted liquid.
Dilute only prior to immediate use.
This affinity-purified antibody is directed against human ATG13 protein.
A BLAST analysis suggests cross-reactivity with ATG13 from human based on 100% sequence homology with the immunogen.
Reactivity against homologues from other sources is not known.
Target Information
Autophagy is a process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway, essential for normal growth control and nutrient preservation under starvation conditions.
ATG13 forms a complex with ULK1, ULK2, and FIP200, and is regulated by TOR (Target of rapamycin).
Inhibition of TOR by rapamycin or leucine deprivation leads to dephosphorylation of ATG13, ULK1, and ULK2, inducing autophagy.
Knockdown of ATG13 inhibits autophagosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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