Thermo Fisher Scientific ABCC8 Polyclonal Antibody
ABCC8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot 및 Immunohistochemistry에 적합합니다. 인간 종에 반응하며, 합성 펩타이드 항원을 사용했습니다. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
- 카탈로그번호
- OSA00225W-100UL
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 1500–1581 of human ABCC8 conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C for short term. For long-term storage, keep at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: ABCC8
Target Information
The protein encoded by the ABCC8 gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across cellular membranes and are divided into seven subfamilies.
This protein is part of the MRP subfamily, involved in multi-drug resistance, and functions as a modulator of ATP-sensitive potassium channels and insulin release.
Mutations and deficiencies are associated with hyperinsulinemic hypoglycemia of infancy and type II diabetes mellitus.
Alternative splicing has been observed, but transcript variants are not fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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