Thermo Fisher Scientific Melanoma Discriminated Antigen Monoclonal Antibody (PAL-M1)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

1:5-1:25

-

Flow Cytometry (Flow)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

PAL-M1

Immunogen

Human melanoma metastases tissue

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

10mM sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_1076665

Product Specific Information

Antibody PAL-M1 stains the majority of primary melanomas and the large majority of metastases and is directed against the transferrin receptor (CD71). Local staining of dysplastic nevocellular nevi may be observed. Common nevocellular nevi rarely stain.

Target Information

Melanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a thickness of greater than 1 mm.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.