Thermo Fisher Scientific Melanoma Discriminated Antigen Monoclonal Antibody (PAL-M2)

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody stains a minority of primary melanomas and approximately half of the metastatic lesions tested. It rarely stains dysplastic naevi or common cellular naevi under standard immunohistochemical conditions. In immunoblotting, the antibody recognizes two protein bands with molecular weights of approximately 95–100 kDa.

Target Information

Melanoma is a malignant tumor of melanocytes, which are predominantly found in the skin but also in the bowel and eye (see uveal melanoma). Although it is one of the rarer types of skin cancer, it accounts for the majority of skin cancer-related deaths. Despite extensive research, the only effective cure remains surgical resection of the primary tumor before it exceeds 1 mm in thickness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.