Thermo Fisher Scientific Melanoma Discriminated Antigen Monoclonal Antibody (PAL-M2)

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

1:20

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

PAL-M2

Immunogen

Isolated from Human Melanoma cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

10mM sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_1076667

Product Specific Information

This antibody stains a minority of primary melanomas and half of the metastatic lesions tested. It rarely stains dysplastic naevi or common cellular naevi using standard immunohistochemical conditions. The antibody recognizes two protein bands in immunoblotting with a molecular weight of 95-100 kD.

Target Information

Melanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a thickness of greater than 1 mm.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.