Thermo Fisher Scientific CD3e (T-Cell Marker) Recombinant Rabbit Monoclonal Antibody (C3e/3171R)
CD3e T세포 마커를 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 사람 시료에 반응하며 IHC와 ELISA에 적합. 고순도 Protein A/G 정제, PBS 버퍼에 0.05% BSA 포함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | C3e/3171R |
| Immunogen | Recombinant human CD3e fragment (aa 23–119) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Dog or Cat.
Target Information
CD3 subunit complex plays a crucial role in transducing antigen-recognition signals into T cells and regulating TCR complex expression. The CD3 subunits (gamma, delta, epsilon, zeta) are immunoglobulin superfamily members encoded on chromosome 11. These subunits have cytoplasmic tails with tyrosine-based motifs mediating signal transduction. CD3 is expressed on 68–82% of peripheral blood lymphocytes, 65–85% of thymocytes, and Purkinje cells, but not on B or NK cells. CD3 defects are associated with immunodeficiency and altered T lymphocyte populations in autoimmune diseases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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