Thermo Fisher Scientific IGF2BP3 Monoclonal Antibody (OTI6A3), TrueMAB
IGF2BP3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 검증됨. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 암 연구 및 단백질 발현 분석에 적합.
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Thermo Fisher Scientific IGF2BP3 Monoclonal Antibody (OTI6A3), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC(P)) | 1:150 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A3 |
| Immunogen | Full-length human recombinant protein of human IGF2BP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Insulin-like growth factor-II mRNA-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, belongs to the IGF2 mRNA-binding protein family.
It is expressed during embryogenesis and in certain malignancies. IMP-3 is found in malignant melanoma but not in benign nevi, and its expression correlates with melanoma progression and metastasis.
IMP-3 may play a key role in regulating tumor biological behavior.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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