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Thermo Fisher Scientific Dynamin 1 Polyclonal Antibody
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Dynamin 1 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 immunocytochemistry에 적합하며, rat, mouse, human에서 교차 반응. 고순도 항원 친화 크로마토그래피 정제, -20°C 보관.
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마지막 업데이트 2025. 08. 04. 오후 11:43
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Thermo Fisher Scientific PA1660 Dynamin 1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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708,700원VAT 포함 779,570원
Thermo Fisher Scientific · Thermo Fisher Scientific Dynamin 1 Polyclonal Antibody
Thermo Fisher Scientific Dynamin 1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 14 publications |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 5 publications |
| Immunoprecipitation (IP) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 633–647 of rat Dynamin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_325845 |
Product Specific Information
- Catalog No: PA1-660
- Detects dynamin I (Dyn1) from rat tissues.
- Suitable for Western blot and immunocytochemical procedures.
- Detects ~100 kDa protein representing Dyn1 from rat whole brain extract.
- Immunizing peptide corresponds to amino acid residues 633–647 from rat Dyn1, conserved in rat, mouse, and human.
- Immunizing peptide (Cat. # PEP-042) available for neutralization and control experiments.
Target Information
Dynamin is a GTPase required for endocytosis of clathrin-coated vesicles from the membrane. Its role in endocytosis was first identified in Drosophila melanogaster.
Three isoforms exist in mammals:
- Dynamin 1: Expressed in neurons
- Dynamin 2: Ubiquitously expressed
- Dynamin 3: Expressed primarily in testes
Each isoform has multiple splice variants, suggesting distinct intracellular functions.
Common structural domains include:
- N-terminal GTPase domain
- Central pleckstrin homology domain
- C-terminal proline-rich region with SH3 domains
Dynamin interacts with AP2 adaptor protein complex and amphiphysin, targeting clathrin-coated pits.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
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