Thermo Fisher Scientific Dynamin 2 Polyclonal Antibody
Dynamin 2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF 등 다양한 응용에 적합함. 인간, 마우스, 랫트 반응성. 1 mg/mL 농도의 액상 형태로 공급되며 PBS/BSA 완충액에 보존. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Dynamin 2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2–4 µg/mL | View 14 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100 | View 3 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: C S(760) P T P Q R R P V S S I H P P G R P P A(779) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2293040 |
Product Specific Information
PA1-661 detects dynamin II (Dyn2) from rat, mouse, and human tissues and cells.
It has been successfully used in Western blot procedures, detecting an approximately 100 kDa Dyn2 protein from HeLa cell lysate.
The immunizing peptide corresponds to amino acid residues 760–779 of human Dyn2, which is 95% conserved in mouse and rat Dyn2.
The immunizing peptide (Cat. # PEP-056) is available for use in neutralization and control experiments.
Target Information
Dynamins are a subfamily of GTP-binding proteins sharing sequence similarity over the N-terminal GTPase domain.
They are associated with microtubules and play roles in endocytosis, cell motility, and membrane remodeling processes such as osteoclast-mediated bone resorption.
Dynamins interact with actin-binding and other cytoskeletal proteins and can self-assemble to stimulate GTPase activity.
Five alternatively spliced transcripts encoding different proteins have been described; additional variants may exist but are not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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