
Thermo Fisher Scientific MAPK13 Monoclonal Antibody (OTI12B12), TrueMAB
MAPK13 단백질을 인식하는 Mouse 모노클로날 항체로, WB 및 ICC/IF에 적합. 인간, 개, 마우스 반응성. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 연구용으로 세포 신호전달 및 스트레스 반응 연구에 활용 가능.
- 카탈로그번호
- CF505781
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:200–1:2,000
- Immunocytochemistry (ICC/IF): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI12B12 |
| Immunogen | Full length human recombinant protein of human MAPK13 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of ~1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MAPK13 (p38 delta) is a serine/threonine kinase involved in transducing extracellular signals such as cytokine and environmental stress responses. It regulates keratinocyte differentiation and is activated by phosphorylation or interaction with MAP3K7IP1/TAB1. Substrates include ATF2, MEF2C, MAX, CDC25B, and p53, indicating roles in transcriptional regulation, cell cycle control, and genotoxic stress response. Four alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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