Thermo Fisher Scientific BBOX1 Monoclonal Antibody (OTI8B12), TrueMAB
BBOX1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS buffer에 trehalose 포함, 보존제 없음. 연구용으로 L-carnitine 생합성 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B12 |
| Immunogen | Full length human recombinant protein of human BBOX1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
BBOX1 encodes gamma butyrobetaine hydroxylase, an enzyme that catalyzes the formation of L-carnitine from gamma-butyrobetaine — the final step in the L-carnitine biosynthetic pathway.
Carnitine is essential for transporting activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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