Thermo Fisher Scientific FN1 Monoclonal Antibody (OTI5C1), TrueMAB
Human FN1 단백질(aa 32-307)을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 적용 가능. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보관. 세포 부착, 이동 및 종양 관련 연구에 적합한 연구용 항체.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FN1 Monoclonal Antibody (OTI5C1), TrueMAB
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 32–307 of human FN1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Fibronectin (FN1) is a disulfide-bonded dimer (230–250 kDa) found in the extracellular matrix and plasma. It forms insoluble polymers through interchain disulfide bonds and plays key roles in:
- Cell adhesion and migration
- Embryogenesis and wound healing
- Blood coagulation and host defense
- Tumor development and metastasis
Fibronectin expression is elevated in non-small cell lung carcinoma, enhancing tumorigenicity and resistance to apoptosis.
The FN1 gene undergoes alternative splicing, potentially producing up to 20 transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.