Thermo Fisher Scientific Haloperidol Monoclonal Antibody (HAL101)

Applications

Tested Dilution

Publications

Inhibition Assays (IA)

Assay-dependent

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

HAL101

Immunogen

Haloperidol conjugated through the tertiary alcohol at the 4` position of the piperidine ring with a succinic acid linkage to keyhole limpet hemocyanin (KLH).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.0 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

2-8°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Haloperidol is a phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity. [National Center for Biotechnology Information. PubChem Compound Database; CID=3559].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.