Thermo Fisher Scientific Haloperidol Monoclonal Antibody (HAL101)
Haloperidol에 특이적인 단클론 항체로, 억제 분석(Inhibition Assay)에 적합. 마우스 IgG1 형식으로 제작되었으며, Protein A로 정제됨. PBS(pH 7.4) 버퍼에 보존제 없이 보관. 연구용으로만 사용 가능.
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Applications
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HAL101 |
| Immunogen | Haloperidol conjugated through the tertiary alcohol at the 4′ position of the piperidine ring with a succinic acid linkage to keyhole limpet hemocyanin (KLH). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 2–8 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Haloperidol is a phenylbutylpiperidine derivative with antipsychotic, neuroleptic, and antiemetic activities. It competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, reducing dopamine neurotransmission and producing antidelusionary and antihallucinogenic effects. Antagonistic activity at D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic action.
(Source: National Center for Biotechnology Information, PubChem Compound Database; CID=3559)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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