Thermo Fisher Scientific F4/80 Monoclonal Antibody (Cl:A3-1), FITC
F4/80 단백질을 표적하는 마우스 유래 단핵구/대식세포 표지용 항체. FITC 형광 표지로 유세포분석(Flow Cytometry) 및 면역형광(ICC/IF)에 적합. Protein G로 정제된 액상 형태이며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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- MA51662x (2개 옵션)
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카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific F4/80 Monoclonal Antibody (Cl:A3-1), FITC
Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Neat
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Cl:A3-1 |
| Immunogen | Thioglycollate-stimulated peritoneal macrophages from C57BL/6 mice |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538123 |
Additional Formats
- Unconjugated (Cat. MA5-16624)
- APC (Cat. MA5-16625)
- Biotin (Cat. MA5-16626)
- PE (Cat. MA5-16631)
- Custom conjugation available upon request
Product Specific Information
- For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
- Rat anti-mouse F4/80 antibody (clone Cl:A3-1) recognizes the murine F4/80 antigen, an approximately 160 kDa cell surface glycoprotein of the EGF-TM7 family.
- The F4/80 antigen shares 68% amino acid identity with human EMR1 (EGF module-containing mucin-like hormone receptor 1).
Target Information
F4/80 antigen is a 160 kDa cell surface glycoprotein belonging to the EGF-TM7 family. It shares 68% amino acid identity with human EMR1. Expression of F4/80 varies during macrophage maturation and activation and is found on various mature tissue macrophages, including Kupffer cells, Langerhans cells, microglia, and macrophages in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma, and spleen red pulp. It may also be expressed on a subset of dendritic cells but is absent from macrophages in T-cell areas of spleen and lymph nodes. The biological function is not fully defined, but studies suggest a role in generating efferent CD8⁺ regulatory T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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