Thermo Fisher Scientific C5AR1 Monoclonal Antibody (P12/1), PE
인간 C5a 수용체(CD88)를 인식하는 마우스 단클론 항체로, PE 형광체로 결합되어 유세포 분석(Flow Cytometry)에 적합. 단백질 G로 정제되었으며, 동결 건조 형태로 제공. 4°C 암소 보관, 재구성 후 사용 가능.
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Applications
- Flow Cytometry (Flow): Neat
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | P12/1 |
| Immunogen | C5aR peptide Met1–Asn31 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Purification | Protein G |
| Storage Buffer | PBS with 5% sucrose, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745081 |
Additional Formats
Product Specific Information
Mouse anti-Human CD88 antibody, clone P12/1 recognizes the C5a receptor (C5aR), also known as CD88 or C5a anaphylatoxin chemotactic receptor 1.
Reconstitute with 1.0 mL distilled water.
Target Information
CD88 (C5aR1) is a C5a Anaphylatoxin Receptor mediating the effects of one of the most potent chemotactic agents known. C5AR1 has been implicated in asthma and is expressed in myeloid blood cells, brain, liver, lung, spleen, heart, kidney, and intestinal tract.
Functionally, CD88 stimulates chemotaxis, granule enzyme release, and superoxide anion production. It is also part of the classical complement pathway and may be involved in tissue injury associated with ischemia or sepsis.
Diseases associated with CD88 include Mannose-Binding Lectin Deficiency and Systemic Lupus Erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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