Thermo Fisher Scientific H3K18ac Polyclonal Antibody
H3K18ac 폴리클로날 항체로, 인간·마우스·랫트 조직에서 히스톤 H3의 Lys18 아세틸화를 검출. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체. -20°C 보관, 방부제 없음.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:800 |
| Immunocytochemistry (ICC/IF) | 1:250 |
| Peptide Array (Array) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic acetylated peptide corresponding to residues surrounding Lys18 of human histone H3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 27 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977245 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other acetylated histones.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells.
H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome.
Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
Post-translational modifications of histones, such as methylation, acetylation, and phosphorylation, regulate chromatin structure and transcription factor binding.
The N-terminal tail of histone H3 can undergo these modifications, influencing multiple cellular processes.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지: PA5-17801_H3K18ac_P68431-1_Rabbit.svg, PA5-17801_H3K18ac_Q71DI3-1_Rabbit.svg, PA5-17801_H3K18ac_P68431-1_Rabbit_PDP.jpeg, PA5-17801_H3K18ac_Q71DI3-1_Rabbit_PDP.jpeg)
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