Thermo Fisher Scientific BCL2A1 Polyclonal Antibody
Human BCL2A1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합. 항원은 BCL2A1(aa118-168) 유래 합성 펩타이드. 액상 형태, 1 mg/mL 농도, PBS+50% glycerol 저장. -20°C 보관, Wet ice 배송.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: []
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:200–1:500
- Publications: []
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BCL2A1 (Accession Q16548), corresponding to amino acid residues I118–L168 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852253 |
Product Specific Information
Antibody detects endogenous levels of total BCL2A1.
Target Information
Bcl-2 related Protein A1 is a member of the BCL-2 protein family. These proteins form hetero- or homodimers and act as anti- and pro-apoptotic regulators involved in various cellular activities such as embryonic development, homeostasis, and tumorigenesis.
This protein reduces the release of pro-apoptotic cytochrome c from mitochondria and blocks caspase activation.
The gene is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by signals like GM-CSF, CD40, phorbol ester, TNF, and IL-1, suggesting a cytoprotective role essential for lymphocyte activation and cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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