Thermo Fisher Scientific PPP1R1A Polyclonal Antibody
PPP1R1A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 비인간 영장류 반응성을 가지며, 액상 형태로 제공되고 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5102875
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PPP1R1A Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PPP1R1A (Accession Q13522), corresponding to amino acid residues G128–V171 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852258 |
Product Specific Information
Antibody detects endogenous levels of total PPP1R1A.
Target Information
Protein phosphatase inhibitor-1 (also designated inhibitor of protein phosphatase 1, IPP-1, and I-1) regulates phosphorylation of other proteins and is phosphorylated by cyclic AMP-dependent protein kinase at Threonine 35.
Cdk1, Cdk5, and MAPK mediate in vitro phosphorylation at Serine 67.
In striatal tissues, glutamate-dependent regulation of NMDA-type channels influences IPP-1 phosphorylation at Ser 67.
Localization and expression suggest discrete roles in brain development, independent of PP-1 regulation.
IPP-1 binds both phosphorylated and dephosphorylated PP-1 and modulates glycogen phosphorylase activity, contributing to hormonal control of glycogen metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.