Thermo Fisher Scientific TYRP1 Recombinant Mouse Monoclonal Antibody (TA99)
Tyrosinase-related protein-1(TRP-1)을 인식하는 재조합 Mouse Monoclonal Antibody(TA99). 멜라닌 생합성 연구용으로 적합하며, 다양한 면역분석(WB, IHC, ICC, ELISA 등)에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적 보관 가능.
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Thermo Fisher Scientific TYRP1 Recombinant Mouse Monoclonal Antibody (TA99)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TA99 |
| Immunogen | 70–75 kDa pigmentation-associated glycoprotein in human melanoma cell lines |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody binds Tyrosinase-related protein-1 (TRP-1), a 70–75 kDa enzyme located in melanocytes. TRP-1 stabilizes tyrosinase, which catalyzes the first step in melanin production, and determines the structure of melanosomes, the organelles where melanin is synthesized.
Target Information
The TYRP1 gene encodes a melanosomal enzyme belonging to the tyrosinase family, playing a key role in the melanin biosynthetic pathway. Mutations in this gene are associated with rufous oculocutaneous albinism and oculocutaneous albinism type III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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