Thermo Fisher Scientific VRK1 Monoclonal Antibody (OTI2E10), TrueMAB
Human VRK1 단백질(aa 1-230)을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 적합. Lyophilized 형태이며 PBS/trehalose buffer에 보존. 연구용으로 p53 신호 경로 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–230 of human VRK1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Human vaccinia-related kinase 1 (VRK1) is a kinase related to a poxvirus kinase and distantly to the casein kinase 1 family.
VRK1 exhibits strong autophosphorylation activity on Ser and Thr residues and acts as an upstream regulator of p53, forming part of a novel signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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