Thermo Fisher Scientific Cytokeratin 1 Recombinant Rabbit Monoclonal Antibody (SN72-08)
Cytokeratin 1을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. HEK293 세포 발현, Protein A 정제, TBS buffer 기반. 높은 특이성과 재현성을 제공하며, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400–1:1,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN72-08 |
| Immunogen | Synthetic peptide within mouse Cytokeratin 1 (aa 586–637) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809583 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
Cytokeratins are intermediate filament proteins exhibiting remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
They vary in molecular weight (approximately 40–68 kDa) and isoelectric point (pH 4.9–7.8).
Expression patterns of cytokeratin subtypes are characteristic of epithelial type and differentiation stage, aiding in distinguishing epithelial malignancies.
Cytokeratin antibodies are valuable tools in tumor differential diagnosis, cytopathology, and flow cytometry.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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