Thermo Fisher Scientific JNK1 Recombinant Polyclonal Antibody (2HCLC)
JNK1 단백질을 인식하는 재조합 폴리클로날 항체로, WB 및 IHC(P)에서 검증됨. 토끼 유래 IgG 형식으로 높은 특이성과 재현성을 제공. 단백질 발현 및 신호전달 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 2HCLC |
| Immunogen | Recombinant protein corresponding to amino acids 17–126 of human JNK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Wet or Dry ice (international) |
| RRID | AB_2532544 |
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Recombinant rabbit polyclonal antibodies from Thermo Fisher Scientific combine multiple recombinant monoclonal antibodies, offering the sensitivity of polyclonal antibodies and the specificity and consistency of monoclonal antibodies.
These antibodies recognize multiple epitopes, providing higher detection sensitivity for low-abundance targets. Recombinant production ensures lot-to-lot consistency by eliminating biological variability.
Target Information
MAPK8 (JNK1) is activated by misfolded proteins in the endoplasmic reticulum and plays a key role in insulin resistance and obesity. It belongs to the MAPK superfamily of stress-activated protein kinases.
MAPKs are serine-threonine protein kinases activated by various extracellular stimuli, mediating signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals. JNK exists in ten isoforms due to mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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