
Thermo Fisher Scientific slo beta 3 (KCNMB3) (extracellular) Polyclonal Antibody
slo beta 3 (KCNMB3) 단백질의 세포외 루프를 인식하는 폴리클로날 항체로, WB 및 IHC(F) 실험에 사용 가능. Mouse와 Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되어 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:300 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)HYDEEAIRTNPK, corresponding to amino acid residues 134–145 of rat KCNMB3, Extracellular loop |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 50 µL or 0.2 mL of double distilled water (DDW) depending on sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For long-term storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
MaxiK channels are large conductance, voltage- and calcium-sensitive potassium channels that regulate smooth muscle tone and neuronal excitability. These channels consist of a pore-forming alpha subunit and a modulatory beta subunit. The KCNMB3 gene encodes a beta subunit that can partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Multiple transcript variants exist due to alternative splicing. A related pseudogene is located on chromosome 22.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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