Thermo Fisher Scientific Transferrin Recombinant Mouse Monoclonal Antibody (TW4.20)
인체 트랜스페린의 N-말단 도메인에 특이적으로 결합하는 재조합 마우스 단클론 항체. Western blot, Flow cytometry, ELISA, Inhibition assay 등 다양한 어세이에 사용 가능. HEK293 세포에서 발현된 IgG1 형 항체로, Protein A로 정제되어 높은 순도 유지.
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- MA548034
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- pk
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Thermo Fisher Scientific Transferrin Recombinant Mouse Monoclonal Antibody (TW4.20)
Applications
- Western Blot (WB): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- ELISA (ELISA): Assay-dependent
- Inhibition Assays (IA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TW4.20 |
| Immunogen | Iron-free purified human transferrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074477 |
Product Specific Information
Specificity: Binds to the N-terminal domain of human transferrin.
Target Information
Transferrins (Tf) are approximately 80 kDa blood plasma glycoproteins synthesized by the liver. They are iron-binding transport proteins that can bind two Fe(3+) ions with an associated anion, usually bicarbonate. Transferrin is responsible for transporting iron from sites of absorption and heme degradation to storage and utilization sites. Under normal conditions, about one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels serves as an indicator for iron-carrying capacity and abnormalities in iron metabolism such as anemia, iron overload, and hemochromatosis. Serum transferrin may also play a role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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