Thermo Fisher Scientific Phl p 1 Chimeric Recombinant Rabbit Monoclonal Antibody (Clone 25)
Phl p 1 풀 꽃가루 알레르겐을 인식하는 키메릭 재조합 토끼 단일클론 항체. Western blot, ELISA, Dot blot 등 다양한 면역실험에 사용 가능. HEK293 세포에서 발현된 Recombinant IgG 항체로 높은 특이성과 재현성을 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Phl p 1 Chimeric Recombinant Rabbit Monoclonal Antibody (Clone 25)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| ELISA | 0.1 ng/mL |
| Dot blot (DB) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Plant |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Clone 25 |
| Immunogen | Recombinant Phl p 1, a grass pollen allergen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3074476 |
Product Specific Information
This antibody binds to the Timothy grass allergen Phl p 1 and shows cross-reactivity with natural group 1 allergens from various grass species such as oat, sweet vernal grass, Bermuda grass, rye grass, common reed, Kentucky blue grass, rye, wheat, and maize (weak).
Target Information
Phl p 1 binds to specific receptors on immune cell surfaces, including TLR4 (Toll-like receptor 4) and MD-2 (myeloid differentiation factor 2). This interaction activates immune cells and triggers inflammatory mediator release, leading to allergic symptoms. The Phl p 1–TLR4–MD-2 interaction is a key event in grass pollen allergy development and is an important target for therapeutic research.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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