Thermo Fisher Scientific PolA1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human POLA1 (DNA polymerase alpha catalytic subunit). Validated for WB and IP applications. Supplied as a liquid, unconjugated form at 0.20 mg/mL. Recommended storage at 4°C and 1-year shelf life.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
- Publications: [References not provided]
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 775 and 825 of Human Polymerase (DNA directed), Alpha 1, Catalytic Subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
DNA replication, recombination, and repair—essential for genomic stability—require exonucleases. These enzymes process Okazaki fragments during replication and excise damaged DNA during repair. DNA polymerases (alpha, beta, delta, epsilon) participate in these processes.
DNA pol delta and epsilon are multisubunit enzymes; DNA pol delta includes p125 and p50 subunits.
DNA pol gamma replicates mitochondrial DNA, while DNA pol zeta mediates damage-induced mutagenesis.
DNA pol theta acts as a polymerase-helicase involved in interstrand crosslink repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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