Thermo Fisher Scientific PolA1 Polyclonal Antibody
Rabbit polyclonal antibody recognizing human PolA1 catalytic subunit. Validated for WB and IP applications. Supplied as liquid, unconjugated form at 0.2 mg/mL. Recommended storage at 4°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1175 and 1225 of Human Polymerase (DNA directed), Alpha 1, Catalytic Subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
DNA replication, recombination, and repair, all essential for genomic stability, require exonucleases. In DNA replication, these enzymes process Okazaki fragments; in DNA repair, they excise damaged DNA and correct mismatches. DNA polymerases alpha, beta, delta, and epsilon are key to these processes. DNA polymerase delta and epsilon are multisubunit enzymes; delta includes subunits p125 (interacting with PCNA) and p50. DNA polymerase gamma replicates mitochondrial DNA. DNA polymerase zeta is widely expressed and mediates damage-induced mutagenesis, while DNA polymerase theta functions as a polymerase-helicase involved in interstrand crosslink repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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