Thermo Fisher Scientific PolA1 Polyclonal Antibody
PolA1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1175 and 1225 of Human Polymerase (DNA directed), Alpha 1, Catalytic Subunit |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
DNA replication, recombination, and repair processes essential for genomic stability require exonucleases.
In DNA replication, these enzymes process Okazaki fragments, while in DNA repair they remove damaged DNA and correct mismatches.
The DNA polymerase family (alpha, beta, delta, epsilon) is involved in these processes.
- DNA pol delta and DNA pol epsilon are multisubunit enzymes; DNA pol delta includes subunits p125 and p50.
- DNA pol gamma replicates mitochondrial DNA.
- DNA pol zeta is widely expressed and mediates damage-induced mutagenesis.
- DNA pol theta functions as a DNA polymerase-helicase involved in interstrand crosslink repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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