Thermo Fisher Scientific p38 MAPK beta Monoclonal Antibody (P38-11A5)
p38 MAPK beta 단백질을 특이적으로 인식하는 마우스 단클론 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능하며, Human과 Mouse 시료에 반응합니다. 단백질 A로 정제된 액상 형태로, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | 14 publications |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | - |
| Immunocytochemistry (ICC/IF) | 1 µg/mL | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | 3 publications |
| Miscellaneous PubMed (Misc) | - | 1 publication |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse, Rabbit |
| Host / Isotype | Mouse / IgG1, IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | P38-11A5 |
| Immunogen | Recombinant full-length human p38 beta-2 (product of the p38-beta gene) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533144 |
Product Specific Information
- Catalog No. 33-8700 has been successfully used in immunofluorescence and western blot.
- Specifically recognizes the beta isoform of p38, with slight reactivity to p38-gamma.
Target Information
MAPK11 (p38 beta) is a serine/threonine kinase involved in various cellular processes and is activated by proinflammatory cytokines and environmental stress.
This protein belongs to the MAP kinase family, which integrates multiple biochemical signals related to proliferation, differentiation, transcription regulation, and development.
p38 MAPK beta is closely related to p38 MAP kinase and is activated through phosphorylation by MAP kinase kinases (MKKs), preferably MKK6.
Transcription factor ATF2/CREB2 has been identified as a substrate of this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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