Thermo Fisher Scientific p38 MAPK beta Monoclonal Antibody (P38-11A5)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

View 14 publications 14 publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:100

-

Immunocytochemistry (ICC/IF)

1 µg/mL

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

View 3 publications 3 publications

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse, Rabbit

Host/Isotype

Mouse / IgG1/IgG2a

Class

Monoclonal

Type

Antibody

Clone

P38-11A5

Immunogen

Recombinant, full-length human p38 beta-2; the product of the p38-beta gene if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:p38 MAPK beta,uniProtId:Q15759-1,ncbiNodeId:9606,antigenRange:1-364,antigenLength:364,antigenImageFileName:33-8700_p38_MAPK_beta_Q15759-1_House_mouse.svg,antigenImageFileNamePDP:33-8700_p38_MAPK_beta_Q15759-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533144

Product Specific Information

33-8700 has been successfully used in immunofluorescence and western blot.

33-8700 specifically recognizes the beta isoform of p38, with slight reactivity to p38-gamma.

Target Information

MAPK11 (p38 beta) is a serine/threonine kinase which is involved in a variety of cellular processes, and is activated by proinflammatory cytokines and environmental stress. Mitogen-activated protein kinase 11. The protein encoded by p38 MAPK beta is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.