Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI4F11)
GORAB 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간 시료 반응성, Mouse IgG1 아이소타입, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F11 |
| Immunogen | Human recombinant protein fragment (aa 35–394 of GORAB) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724384 |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. The SIII complex consists of elongins A/A2, B, and C, and it activates RNA polymerase II elongation by suppressing transient pausing during transcription.
Elongin A serves as the active component, while elongins B and C act as regulatory subunits. Elongin A2 is expressed specifically in the testis and forms a stable complex with elongins B and C.
The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation. Western blot analyses using two different antibodies targeting unique regions of this protein confirmed consistent molecular weight results.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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