Thermo Fisher Scientific GORAB Monoclonal Antibody (OTI1E3)
GORAB 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 다양한 종에 반응하며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–394 of GORAB produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724383 |
Target Information
TCEB1, also known as protein elongin C, is a subunit of the transcription factor B (SIII) complex. The SIII complex consists of elongins A/A2, B, and C, which activate elongation by RNA polymerase II by suppressing transient pausing of the polymerase during transcription.
Elongin A serves as the transcriptionally active component, while elongins B and C act as regulatory subunits.
Elongin A2 is testis-specific and can form a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, inhibiting transcription elongation.
Western blot analyses using two different antibodies targeting distinct regions of this protein confirm consistent molecular weight results.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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