Thermo Fisher Scientific Kappa Light Chain Monoclonal Antibody (A8H10)
인간 Kappa Light Chain을 인식하는 Mouse monoclonal antibody(A8H10). Western blot과 IHC(Paraffin)에 적합. 단백질 A로 정제된 2 mg/mL 액상 시약으로, PBS 기반 buffer에 0.05% sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A8H10 |
| Immunogen | Recombinant full protein within human IGKC aa 1–107/107 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3094365 |
Product Specific Information
- Positive control: Human tonsil tissue, human appendix tissue
- Predicted band size: 11.7 kDa
- Subcellular Location: Cell membrane, Secreted
Target Information
Immunoglobulin classes share a basic structure of two heavy chains and two light chains (kappa, lambda).
Kappa and lambda chains (22.5 kDa each) consist of variable and constant regions, distinguishable by antigenic properties.
The kappa to lambda ratio is approximately 70:30.
Antibodies to the kappa light chain are useful for identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Detection of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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