Thermo Fisher Scientific Aprataxin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:100

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 93-342 of human APTX (NP_0011821781) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Aprataxin,uniProtId:Q7Z2E3-1,ncbiNodeId:9606,antigenRange:93-342,antigenLength:356,antigenImageFileName:PA5-92422_Aprataxin_Q7Z2E3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-92422_Aprataxin_Q7Z2E3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.47 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806489

Product Specific Information

Immunogen sequence: LYPYIVEFEE EAKNPGLETH RKRKRSGNSD SIERDAAQEA EAGTGLEPGS NSGQCSVPLK KGKDAPIKKE SLGHWSQGLK ISMQDPKMQV YKDEQVVVIK DKYPKARYHW LVLPWTSISS LKAVAREHLE LLKHMHTVGE KVIVDFAGSS KLRFRLGYHA IPSMSHVHLH VISQDFDSPC LKNKKHWNSF NTEYFLESQA VIEMVQEAGR VTVRDGMPEL LKLPLRCHEC QQLLPSIPQL KEHLRKHWTQ; Positive Samples: 22Rv1, A-549, K-562, BT-474, U-87MG, HT-29, Raji; Cellular Location: Cytoplasm, Nucleus, nucleolus, nucleoplasm

Target Information

This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.