Thermo Fisher Scientific Syntenin 1 Polyclonal Antibody
Thermo Fisher Scientific의 Syntenin 1 Polyclonal Antibody는 인간 단백질을 타겟으로 하는 Rabbit IgG 항체입니다. Western blot, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 연구용으로 사용됩니다.
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- PA592419
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–260 of human Syntenin (NP_0010070681) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.19 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806487 |
Product Specific Information
Immunogen sequence:
MSLYPSLEDL KVDKVIQAQT AFSANPANPA ILSEASAPIP HDGNLYPRLY PELSQYMGLS LNEEEIRANV AVVSGAPLQG QLVARPSSIN YMVAPVTGND VGIRRAEIKQ GIREVILCKD QDGKIGLRLK SIDNGIFVQL VQANSPASLV GLRFGDQVLQ INGENCAGWS SDKAHKVLKQ AFGEKITMTI RDRPFERTIT MHKDSTGHVG FIFKNGKITS IVKDSSAARN GLLTEHNICE INGQNVIGLK DSQIADILST
Positive Samples: HT-29, THP-1
Cellular Location: Cell junction, Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Melanosome, Nucleus, Peripheral membrane protein, adherens junction, cytoskeleton, cytosol, focal adhesion
Target Information
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and activation of transcription factors. It is primarily localized to membrane-associated adherens junctions and focal adhesions, but also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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