Thermo Fisher Scientific Human SH3BP4 Synthetic Peptide
인간 SH3BP4 단백질의 C-말단 18개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-20747의 블로킹 펩타이드로 사용 가능. 순도 높은 액상 형태로 제공되며 PBS 완충액에 0.1% BSA 포함. 연구용으로만 사용 가능.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human SH3BP4.
PEP-0861 can be used as a blocking peptide with polyclonal antibody PA5-20747.
Target Information
SH3BP4 was initially isolated as a novel cDNA using differential display analysis with cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site.
SH3BP4 interacts with endocytic proteins such as clathrin, dynamin, and transferrin receptor (TfR), localizing to TfR-containing coated pits and vesicles. It is involved in cargo-specific control of clathrin-mediated endocytosis, particularly the internalization of TfR. At least two isoforms of SH3BP4 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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