Thermo Fisher Scientific Human ST3GAL6 Synthetic Peptide
Human ST3GAL6 단백질의 16개 아미노산 서열로 구성된 합성 펩타이드입니다. ST3GAL6 항체의 블로킹 펩타이드로 사용 가능하며, 인간 시알릴트랜스퍼라제 연구에 적합합니다. 정제된 액상 형태로 제공되며, PBS 버퍼(pH 7.2)에 0.1% BSA와 0.02% sodium azide를 포함합니다.
- 카탈로그번호
- PEP0862
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Human ST3GAL6 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human ST3GAL6.
PEP-0862 can be used as a blocking peptide with polyclonal antibody PA5-20748.
Target Information
Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups.
Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types.
Cancer cells often express more heavily sialylated glycans on their surface, correlating with invasiveness. In contrast, expression of ST3GAL6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, is significantly decreased by hypermethylation of the gene in gastrointestinal cancer.
At least three isoforms of ST3GAL6 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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