Thermo Fisher Scientific Human C-Reactive Protein (CRP) Recombinant Protein
Recombinant human C-Reactive Protein (CRP) for use as a positive control in immunological assays. Expressed in E. coli with >95% purity. Plays a key role in inflammation and innate immunity. Supplied as liquid, 1 mg/mL concentration, stored at 4°C.
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- RP7552x (2개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
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Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Gln19–Pro224 |
| Molecular Weight | 27.18 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | TBS, pH 7.5, with 0.14 mM NaCl, 2 mM CaCl₂ |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains purified recombinant human C-Reactive Protein (CRP).
It may be used as a positive control in various immunological assays.
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids and has a molecular weight of approximately 24 kDa.
Produced by the liver, CRP levels increase dramatically during inflammatory processes. It initiates the classical complement cascade, binds nuclear components (chromatin, histones), and plays a key role in innate immunity and nonspecific host resistance.
CRP levels can rise 100–1000 fold in response to injury, infection, or inflammation. It acts as an opsonin, activates monocytes/macrophages, and functions as a scavenger during cell necrosis. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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